Coronary Heart Disease Diagnosis under local differential privacy

Context extraction model


Due to the increasing medical data for coronary heart disease (CHD) diagnosis, how to assist doctors to make proper clinical diagnosis has attracted considerable attention. However, it faces many challenges, including personalized diagnosis, high dimensional datasets, clinical privacy concerns and insufficient computing resources. To handle these issues, we propose a novel blockchainenabled contextual online learning model under local differential privacy for CHD diagnosis in mobile edge computing. Various edge nodes in the network can collaborate with each other to achieve information sharing, which guarantees that CHD diagnosis is suitable and reliable. To support the dynamically increasing dataset, we adopt a top-down tree structure to contain medical records which is partitioned adaptively. Furthermore, we consider patients’ contexts (e.g., lifestyle, medical history records, and physical features) to provide more accurate diagnosis. Besides, to protect the privacy of patients and medical transactions without any trusted third party, we utilize the local differential privacy with randomised response mechanism and ensure blockchain-enabled information-sharing authentication under multi-party computation. Based on the theoretical analysis, we confirm that we provide real-time and precious CHD diagnosis for patients with sublinear regret, and achieve efficient privacy protection. The experimental results validate that our algorithm outperforms other algorithm benchmarks on running time, error rate and diagnosis accuracy.

Keywords: Blockchain, Big Data, Coronary Heart Disease Diagnosis (CHD), Contextual Online Learning, Edge Computing, Local Differential Privacy


  • To address important issues in personalized diagnosis support, high dimensional datasets, clinical privacy concerns and insufficient computing resources, we propose a novel context-aware online learning algorithm and framework for CHD diagnosis, which considers the heterogeneity of patients to guarantee the real-time personalized diagnosis for patients.
    Workflow of blockchain-enabled contextual online learning system in edge computing for CHD diagnosis.
  • We adopt the local differential privacy method to prevent the privacy of patients from being attacked and utilize the blockchain-enabled model to guarantee the security of diagnosis records sharing and medical transactions.
  • Our proposal is in edge computing to reduce time consumption and space cost, which can process massive data from patients and accelerate the online learning process for CHD diagnosis simultaneously.
Xin Liu
Xin Liu
Ph.D. Student

I am a second-year Ph.D. student in the Department of Computer Science at the University of Virginia. I have interests and skills in software system security, program analysis, differential privacy and machine learning.